CO2 Extraction with Co-Solvents – Enhancing Efficiency & Yield
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CO2 Extraction with Co-Solvents – Enhancing Efficiency & Yield

CO2 extraction is one of the most efficient and cleanest extraction methods, but some bioactive compounds have low solubility in pure CO2. To enhance efficiency, yield, and selectivity, many extraction facilities integrate co-solvents—such as ethanol, methanol, or water—to improve extraction speed, increase compound solubility, and optimize yields.

Using a CO2 SUPERCRITICAL EXTRACTION MACHINE with co-solvents allows manufacturers in pharmaceuticals, cannabis, food, and nutraceuticals to extract higher-purity, higher-yield compounds while maintaining a solvent-free final product.

1. Best Co-Solvents for CO2 Extraction

Co-SolventBest ForAdvantagesRecommended Usage (%)
EthanolCannabis, pharmaceuticals, essential oilsHigh efficiency, food-grade, enhances flavonoid & terpene solubility0.5-5%
MethanolAlkaloids, pharmaceuticalsHigh polarity, effective for plant alkaloids0.1-2%
WaterPolyphenols, antioxidants, food extractsNon-toxic, ideal for delicate plant compounds1-10%
AcetoneLab research, industrial extractionsStrong solvent power, efficient but requires careful post-processing0.1-1%

2. How Co-Solvents Improve CO2 Extraction Efficiency

  • ✅ Enhances Solubility of Polar Compounds – Improves extraction efficiency for flavonoids & polyphenols.
  • ✅ Increases Cannabinoid Yield & Efficiency – 1-5% ethanol enhances CBD & THC extraction by 20-30%.
  • ✅ Reduces CO2 Consumption & Energy Costs – Co-solvents improve efficiency, lowering CO2 usage & energy consumption.

Conclusion

CO2 extraction with co-solvents is the best method for improving efficiency, yield, and bioactive compound purity.

SHANG HAI NORTH BROOKS CO2 SUPERCRITICAL EXTRACTION MACHINES provide state-of-the-art technology, making them the best choice for high-yield, solvent-assisted CO2 extraction.

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