CO2 Extraction vs Solvent Extraction for Pharmaceuticals
来源: | 作者:selina | 发布时间 :2025-03-03 | 70 次浏览: | Share:

CO2 Extraction vs Solvent Extraction for Pharmaceuticals

Pharmaceutical companies require **high-purity extracts** to ensure the safety and effectiveness of medicinal compounds. The two primary extraction methods—supercritical CO2 extraction and solvent extraction—offer different benefits and challenges. This article examines their application in the pharmaceutical industry.

1. Purity and Chemical Safety

  • Supercritical CO2 Extraction: Produces **solvent-free, pharmaceutical-grade extracts**, reducing contamination risks.
  • Solvent Extraction: May leave **trace solvents**, requiring additional purification to meet regulatory standards.

2. Efficiency and Selectivity

  • CO2 Extraction: **Highly selective**, extracting **specific bioactive compounds** while leaving impurities behind.
  • Solvent Extraction: Less selective, sometimes extracting **unwanted fats and waxes**.

3. Regulatory Compliance

  • CO2 Extraction: Approved for **pharmaceutical and medical applications**, ensuring compliance with **FDA and EU GMP standards**.
  • Solvent Extraction: Requires **additional solvent removal** steps to meet safety regulations.

4. Case Study: CO2 Extraction in Pharmaceutical Research

A European pharmaceutical company replaced solvent extraction with CO2 extraction, reducing **solvent waste by 50%** and improving **bioactive compound retention**.

5. Conclusion

For **pharmaceutical-grade extractions**, **supercritical CO2 extraction** ensures higher purity and regulatory compliance. Companies like **SHANGHAI NORTH BROOKS** provide advanced **CO2 SUPERCRITICAL EXTRACTION MACHINE** solutions tailored for pharmaceutical applications.

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